Group Leader and Senior Lecturer in Biochemistry
Knowledge of proteins and other biological macromolecules 3D structures is essential to understand how they work.
Key research questions:
- What are the mechanisms that govern passage of information inside a cell? Can we identify strategies to mimic or regulate them?
- How do proteins recognise different cellular targets, and how is this recognition regulated?
- …ultimately, why does cancer form? What went wrong?
The role of p90 ribosomal S6 kinases (RSKs) in steroid receptor signalling.
Flipping the switch; regulating protein synthesis in response to stress
The Unfolded Protein Response in Prostate Cancer: Developing Novel Strategies for Therapeutic Intervention.
Former Lab Members
Dr Alessandro Sicorello (Postdoctoral Researcher) – now Postdoc at UCL
Dr Vinayakumar Gedi (Postdoctoral Researcher) – now Postdoc at University of Limerick
Eleanor Rees (Research Assistant)
Louise Dunnett (PhD) – now Postdoc at Diamond Light Source
Emma Stanton (MSD) – now PhD at Swansea University
Georgia Taylor (MSD) – now PhD at UCL
Billy Murphy (MSD)