Dr Filippo Prischi
Group Leader and Lecturer in Biochemistry
Knowledge of proteins and other biological macromolecules 3D structures is essential to understand how they work.
Key research questions:
- What are the mechanisms that govern passage of information inside a cell? Can we identify strategies to mimic or regulate them?
- How do proteins recognise different cellular targets, and how is this recognition regulated?
- …ultimately, why does cancer form? What went wrong?
Dr Alessandro Sicorello
Postdoctoral Researcher
Development of specific inhibitors that prevent hnRNPA1-mediated therapy resistance in small cell lung cancer
Ryan Cronin
PhD student
The role of p90 ribosomal S6 kinases (RSKs) in steroid receptor signalling.
Kęstutis Lapėnas
PhD student
Flipping the switch; regulating protein synthesis in response to stress
Ana Maria Isac
PhD student
The Unfolded Protein Response in Prostate Cancer: Developing Novel Strategies for Therapeutic Intervention.
Georgia Taylor
MSD student
High Throughput Drug Screening of a Cancer Target using Room Temperature Serial Crystallography
Billy Murphy
MSD student
Flipping the switch; regulating protein synthesis in response to stress
Emma Stanton
MSD student
Development of novel cancer treatments: structural studies of Nectin 4 in complex with bespoke anti-cancer peptides
Former Lab Members
Dr Vinayakumar Gedi (Postdoctoral Researcher)
Eleanor Rees (Research Assistant)
Louise Dunnett (PhD) – now at Diamond Light Source
