Google Scholar Profile

University of Essex Institutional Repository Service

Selected publications:

• Chrysostomou S*, Roy R*, Prischi F* et al. Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. Science Translational Medicine. 2021; 13:eaba4627.
• Cronin R, Brooke G, Prischi F. The role of the p90 ribosomal S6 kinase family in prostate cancer progression and therapy resistance. Oncogene. 2021; 40:3775–3785.
• Prischi F, Filippakopoulos P. Structural Studies of Protein Complexes in Signaling Pathways. Front. Mol. Biosci. 2021; 8:641932.
• Obomighie I*, Lapenas K*, Murphy B, Bowles A, Bechtold U and Prischi F. The Role of Ribosomal Protein S6 Kinases in Plant Homeostasis. Front. Mol. Biosci. 2021; 8:24.
• Brooke G, Prischi F. Structural and functional modelling of SARS-CoV-2 entry in animal models. Sci Rep. 2020; 10, 15917.
• Trezza A, Iovinelli D, Santucci A, Prischi F & Spiga O. An integrated drug repurposing strategy for the rapid identification of potential SARS-CoV-2 viral inhibitors. Sci Rep. 2020; 10, 13866.
• Prischi F, Pastore A. Hybrid Methods in Iron-Sulfur Cluster Biogenesis. Front. Mol. Biosci. 2017; 4:12.
• Prischi F, Pastore A. Application of Nuclear Magnetic Resonance and Hybrid Methods to Structure Determination of Complex Systems. Adv Exp Med Biol. 2016; 896:351-68.
• Carrara M, Prischi F, Nowak P, Ali MM. Crystal Structures of Perk Luminal Domains Reveal Transient Tetramer State Important for ER Stress Signaling. EMBO J, 2015; 34:1589-1600.
• Carrara M, Prischi F, Nowak P, Kopp MC, Ali MM. Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling. eLife. 2015; 4:e03522.
• Prischi F, Nowak P, Carrara M, Ali MM. Phosphoregulation of human Ire1 RNase splicing activity. Nat. Commun. 2014; 5:3554.