Selected publications:
- Dunnett L, Das S, Venditti V, Prischi
. Enhanced identification of small molecules binding to hnRNPA1 via cryptic pockets mapping coupled with X-Ray fragment screening JBC. 2025;301(4):108335. - Roucairol M, Georgiou A, Cazenave T, Prischi F, Pardo OE. DrugSynthMC: An Atom-Based Generation of Drug-like Molecules with Monte Carlo Search J Chem Inf Model . 2024;64(18):7097-7107.
- Cronin R, Azadova A, Marco A, Laissue PP, Brooke GN, Prischi F. The p90 Ribosomal S6 Kinases 2 and 4 promote Prostate Cancer cell proliferation in androgen-dependent and independent ways bioRxiv, 2024.03. 04.582739
- Chrysostomou S*, Roy R*, Prischi F* et al. Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. Science Translational Medicine. 2021; 13:eaba4627.
- Cronin R, Brooke G, Prischi F. The role of the p90 ribosomal S6 kinase family in prostate cancer progression and therapy resistance. Oncogene. 2021; 40:3775–3785.
- Prischi F, Filippakopoulos P. Structural Studies of Protein Complexes in Signaling Pathways. Front. Mol. Biosci. 2021; 8:641932.
- Obomighie I*, Lapenas K*, Murphy B, Bowles A, Bechtold U and Prischi F. The Role of Ribosomal Protein S6 Kinases in Plant Homeostasis. Front. Mol. Biosci. 2021; 8:24.
- Brooke G, Prischi F. Structural and functional modelling of SARS-CoV-2 entry in animal models. Sci Rep. 2020; 10, 15917.
- Trezza A, Iovinelli D, Santucci A, Prischi F & Spiga O. An integrated drug repurposing strategy for the rapid identification of potential SARS-CoV-2 viral inhibitors. Sci Rep. 2020; 10, 13866.
- Carrara M, Prischi F, Nowak P, Kopp MC, Ali MM. Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling. eLife. 2015; 4:e03522.
- Prischi F, Nowak P, Carrara M, Ali MM. Phosphoregulation of human Ire1 RNase splicing activity. Nat. Commun. 2014; 5:3554.
Prischi Lab 